Quick Overview

Somatropin (as Well As Endogenous Gh) Binds To A Dimeric Gh Receptor In The Cell Membrane Of Target Cells Resulting In Intracellular Signal Transduction And A Host Of Pharmacodynamic Effects. Some Of These Pharmacodynamic Effects Are Primarily Mediated By Igf-i Produced In The Liver And Also Locally (e.g., Skeletal Growth, Protein Synthesis), While Others Are Primarily A Consequence Of The Direct Effects Of Somatropin (e.g., Lipolysis)